In the design of any floating or fixed marine structure, it is vital to test models in order to understand the fluid/structure interaction involved. A relatively inexpensive method, compared to physical model testing, of achieving this is to numerically model the structure and the wave conditions in a numerical wave tank. In this paper, a methodology for accurately replicating measured ocean waves in a numerical model at full scale is detailed. A Fourier analysis of the measured record allows the wave to be defined as a summation of linear waves and, therefore, Airy's linear wave theory may be used to input the wave elevation and associated water particle velocities. Furthermore, a structure is introduced into the model to display the ability of the model to accurately predict wave-structure interaction. A case study of three individual measured waves, which are recorded at the Atlantic marine energy test site, off the west coast of Ireland, is also presented. The accuracy of the model to replicate the measured waves and perform wave-structure interaction is found to be very high. Additionally, the absolute water particle velocity profile below the wave from the numerical model is compared to a filtered analytical approximation of the measured wave at a number of time-steps and is in very good agreement. (C) 2015 Elsevier Ltd. All rights reserved.