Peer-Reviewed Journal Details
Mandatory Fields
Destrade, M,Gilchrist, MD,Murphy, JG,Rashid, B,Saccomandi, G
2015
October
International Journal Of Non-Linear Mechanics
Extreme softness of brain matter in simple shear
Published
()
Optional Fields
Mechanics of brain matter Simple shear Constitutive modelling Experimental testing Simulations Poynting effect TISSUE STRAIN DEFORMATION INJURY MODEL
75
54
58
We show that porcine brain matter can be modelled accurately as a very soft rubber-like material using the Mooney-Rivlin strain energy function, up to strains as high as 60%. This result followed from simple shear experiments performed on small rectangular fresh samples (2.5 cm(3) and 1.1 cm(3)) at quasi-static strain rates. They revealed a linear shear stress-shear strain relationship (R-2 > 0.97), characteristic of Mooney-Rivlin materials at large strains. We found that porcine brain matter is about 30 times less resistant to shear forces than a silicone gel. We also verified experimentally that brain matter exhibits the positive Poynting effect of non-linear elasticity, and numerically that the stress and strain fields remain mostly homogeneous throughout the thickness of the samples in simple shear. (C) 2015 Elsevier Ltd. All rights reserved.
10.1016/j.ijnonlinmec.2015.02.014
Grant Details
Publication Themes
Biomedical Science and Engineering, Informatics, Physical and Computational Sciences