Peer-Reviewed Journal Details
Mandatory Fields
Khan S, Wall D, Curran C, Newell J, Kerin MJ, Dwyer RM
2015
May
BMC Cancer
MicroRNA-10a is reduced in breast cancer and regulated in part through retinoic acid.
Published
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15
1
MicroRNAs (miRNAs) are short non-coding RNA molecules that play a critical role in mRNA cleavage and translational repression, and are known to be altered in many diseases including breast cancer. MicroRNA-10a (miR-10a) has been shown to be deregulated in various cancer types. The aim of this study was to investigate miR-10a expression in breast cancer and to further delineate the role of retinoids and thyroxine in regulation of miR-10a.
10.1186/s12885-015-1374-y
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