Peer-Reviewed Journal Details
Mandatory Fields
Stanley A, Thompson K, Hynes A, Brakebusch C, Quondamatteo F
2014
May
Antioxidants & Redox Signaling
NADPH oxidase complex-derived reactive oxygen species, the actin cytoskeleton, and Rho GTPases in cell migration.
Published
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Optional Fields
20
13
2026
2042
Rho GTPases are historically known to be central regulators of actin cytoskeleton reorganization. This affects many processes including cell migration. In addition, members of the Rac subfamily are known to be involved in reactive oxygen species (ROS) production through the regulation of NADPH oxidase (Nox) activity. This review focuses on relationships between Nox-regulated ROS, Rho GTPases, and cytoskeletal reorganization, in the context of cell migration.
10.1089/ars.2013.5713
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