Conference Contribution Details
Mandatory Fields
Ryder, A.G.
The Bioprocessing Summit.
Fast, easy, and reliable methods for quantifying cell culture media variance and stability: Or…how to taste your super soup.
Renaissance Boston Waterfront Hotel, Boston, Mass., USA
Oral Presentation
Optional Fields
The complex composition of cell culture media means that media are inherently unstable, for example, visible light exposure causes extensive photo-damage which in turn adversely affects cell growth.  This can be significant when transparent bioreactors/media containers are used.  Here we show rapid and effective monitoring of cell culture media variance and stability using Fluorescence excitation-emission matrix spectroscopy combined with multi-way chemometrics and/or Surface Enhanced Raman Scattering (SERS).  First for monitoring media photo-damage (riboflavin-based degradation pathways), and second for identifying media decomposition under normal media storage conditions.
Costs covered by conference organiser.
Publication Themes