Conference Contribution Details
Mandatory Fields
Ryder, A.G.
The Bioprocessing Summit.
Fast, easy, and reliable methods for quantifying cell culture media variance and stability: Or…how to taste your super soup.
Renaissance Boston Waterfront Hotel, Boston, Mass., USA
Oral Presentation
Optional Fields
20-AUG-14
21-AUG-14
The complex composition of cell culture media means that media are inherently unstable, for example, visible light exposure causes extensive photo-damage which in turn adversely affects cell growth.  This can be significant when transparent bioreactors/media containers are used.  Here we show rapid and effective monitoring of cell culture media variance and stability using Fluorescence excitation-emission matrix spectroscopy combined with multi-way chemometrics and/or Surface Enhanced Raman Scattering (SERS).  First for monitoring media photo-damage (riboflavin-based degradation pathways), and second for identifying media decomposition under normal media storage conditions.
Costs covered by conference organiser.
Publication Themes