Peer-Reviewed Journal Details
Mandatory Fields
Cao, HL,Dong, YX,Aied, A,Zhao, TY,Chen, X,Wang, WX,Pandit, A
2014
January
Chemical Communications
Acetal-linked branched poly(dimethyl-aminoethyl methacrylate) as an acid cleavable gene vector with reduced cytotoxicity
Published
WOS: 12 ()
Optional Fields
VINYL OLIGOMER COMBINATION ANTICANCER DRUGS DELIVERY-SYSTEMS BLOCK-COPOLYMER PDMAEMA THERAPY DESIGN
50
15565
15568
An acid labile branched PDMAEMA/acetal copolymer with amino group was synthesized by the DE-ATRP and followed by Michael addition. The degradation of the polymer was strongly pH-dependent. High nucleic acid transfection efficiency with low cytotoxicity was observed compared to its non-degradable copolymer counterpart.
10.1039/c4cc06728b
Grant Details
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