Peer-Reviewed Journal Details
Mandatory Fields
Shen, S.a d and Battersby, S.a and Weaver, M.b and Clark, E.a and Stephens, K.b c and Harmar, A.J.a
2000
Refined mapping of the human serotonin transporter (SLC6A4) gene within 17q11 adjacent to the CPD and NF1 genes
Published
()
Optional Fields
8
1
75
78
The SLC6A4 gene encodes the serotonin transporter, the target of an important class of antidepressant drugs (serotonin selective reuptake inhibitors). Polymorphisms in the SLC6A4 gene have been reported to be associated with susceptibility to depression and other psychiatric disorders. We have constructed a 1 Mb YAC and PAC contig which harbours both: the SLC6A4 and the carboxypeptidase D (CPD) genes. The order of loci within the contig was cen-D17S975-D17S1549-24R-D17S1294-SLC6A4-28L-(CPD, D17S2009, D17S2004)-D17S2120-ter. Both genes were deleted in one of 17 neurofibromatosis type 1 (NF1) patients carrying submicroscopic NF1 contiguous gene deletions..
http://www.scopus.com/inward/record.url?eid=2-s2.0-0033994296&partnerID=40&md5=b46b783127b8ae2bb04a3a2176c98192
Grant Details
Publication Themes