Peer-Reviewed Journal Details
Mandatory Fields
McGovern, RE,McCarthy, AA,Crowley, PB
2014
April
Chemical Communications
Protein assembly mediated by sulfonatocalix[4]arene
Published
()
Optional Fields
RECOGNITION BINDING CALIXARENE LYSOZYME ARGININE LYSINE COMPLEX DIMERIZATION MACROCYCLES CAPSULES
50
10412
10415
A crystal structure of lysozyme in complex with p-sulfonato-calix[4]arene (sclx(4)) reveals a linear assembly of protein tetramers glued together by protein-calixarene interactions. One interaction involves encapsulation of the highly exposed C-terminal Arg128. The other involves an intricate protein-bound complex of sclx(4), Mg2+ and a fragment of polyethylene glycol.
10.1039/c4cc04897k
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