Peer-Reviewed Journal Details
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Molloy, GJ,Messerli-Burgy, N,Hutton, G,Wikman, A,Perkins-Porras, L,Steptoe, A
2014
May
Journal Of Psychosomatic Research
Intentional and unintentional non-adherence to medications following an acute coronary syndrome: A longitudinal study
Published
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Adherence Acute coronary syndrome Psychological Intention SELF-REPORT ADHERENCE BELIEFS METAANALYSIS BEHAVIOR THERAPY ILLNESS
76
430
432
Objective: Non-adherence to medication is common among coronary heart disease patients. Non-adherence to medication may be either intentional or unintentional. In this analysis we provide estimates of intentional and unintentional non-adherence in the year following an acute coronary syndrome (ACS).Method: In this descriptive prospective observational study of patients with confirmed ACS medication adherence measures were derived from responses to the Medication Adherence Report Scale at approximately 2 weeks (n = 223), 6 months (n = 139) and 12 months (n = 136) following discharge from acute treatment for ACS.Results: Total medication non-adherence was 20%, 54% and 53% at each of these time points respectively. The corresponding figures for intentional non-adherence were 8%, 15% and 15% and 15%, 52% and 53% for unintentional non-adherence. There were significant increases in the levels of medication non-adherence between the immediate discharge period (2 weeks) and 6 months that appeared to stabilize between 6 and 12 months after acute treatment for ACS.Conclusion: Unintentional non-adherence to medications may be the primary form of non-adherence in the year following ACS. Interventions delivered early in the post-discharge period may prevent the relatively high levels of non-adherence that appear to become established by 6 months following an ACS. (C) 2014 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).
10.1016/j.jpsychores.2014.02.007
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