Peer-Reviewed Journal Details
Mandatory Fields
McDermott AM, Miller N, Wall D, Martyn LM, Ball G, Sweeney KJ, Kerin MJ
2014
January
Plos One
Identification and Validation of Oncologic miRNA Biomarkers for Luminal A-like Breast Cancer.
Published
Altmetric: 3WOS: 51 ()
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9
1
Breast cancer is a common disease with distinct tumor subtypes phenotypically characterized by ER and HER2/neu receptor status. MiRNAs play regulatory roles in tumor initiation and progression, and altered miRNA expression has been demonstrated in a variety of cancer states presenting the potential for exploitation as cancer biomarkers. Blood provides an excellent medium for biomarker discovery. This study investigated systemic miRNAs differentially expressed in Luminal A-like (ER+PR+HER2/neu-) breast cancer and their effectiveness as oncologic biomarkers in the clinical setting.
10.1371/journal.pone.0087032
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