Peer-Reviewed Journal Details
Mandatory Fields
Fitzpatrick F, Humphreys H, O'Gara JP
2005
April
Journal Of Clinical Microbiology
Evidence for icaADBC-independent biofilm development mechanism in methicillin-resistant Staphylococcus aureus clinical isolates.
Published
Optional Fields
43
4
1973
1976
Synthesis of a polysaccharide adhesin by icaADBC-encoded enzymes is currently the best-understood mechanism of staphylococcal biofilm development. In four methicillin-resistant Staphylococcus aureus isolates, environmental activation of icaADBC did not always correlate with increased biofilm production. Moreover, glucose-mediated biofilm development in these isolates was icaADBC independent. Apparently, an environmentally regulated, ica-independent mechanism(s) of biofilm development exists in S. aureus clinical isolates.
10.1128/JCM.43.4.1973-1976.2005
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