Peer-Reviewed Journal Details
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Donohoe G, Morris DW, De Sanctis P, Magno E, Montesi JL, Garavan HP, Robertson IH, Javitt DC, Gill M, Corvin AP, Foxe JJ
2008
March
Biological Psychiatry
Early visual processing deficits in dysbindin-associated schizophrenia.
Published
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63
5
484
489
Variation at the dysbindin gene (DTNBP1) has been associated with increased risk for schizophrenia in numerous independent samples and recently with deficits in general and domain-specific cognitive processing. The relationship between dysbindin risk variants and sensory-level deficits in schizophrenia remains to be explored. We investigated P1 performance, a component of early visual processing on which both patients and their relatives show deficits, in carriers and noncarriers of a known dysbindin risk haplotype.
http://www.ncbi.nlm.nih.gov/pubmed/17945199
10.1016/j.biopsych.2007.07.022
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