Peer-Reviewed Journal Details
Mandatory Fields
Chonghaile MN, Higgins BD, Costello J, Laffey JG
2008
November
Anesthesiology
Hypercapnic acidosis attenuates lung injury induced by established bacterial pneumonia.
Published
()
Optional Fields
109
5
837
848
Hypercapnic acidosis protects against lung injury after ischemia-reperfusion, endotoxin-induced and ventilation-induced lung injury. The effects of hypercapnic acidosis in the setting of established pulmonary sepsis are not known. The authors investigated whether hypercapnic acidosis -- induced by adding carbon dioxide to inspired gas -- would be beneficial or deleterious in established Escherichia coli pneumonia in an in vivo model, in the presence and absence of antibiotic therapy.
10.1097/ALN.0b013e3181895fb7
Grant Details
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