Peer-Reviewed Journal Details
Mandatory Fields
O'Toole D, Hassett P, Contreras M, Higgins BD, McKeown ST, McAuley DF, O'Brien T, Laffey JG
2009
November
Thorax
Hypercapnic acidosis attenuates pulmonary epithelial wound repair by an NF-kappaB dependent mechanism.
Published
WOS: 64 ()
Optional Fields
64
11
976
982
Hypercapnic acidosis exerts protective effects in acute lung injury but may also slow cellular repair. These effects may be mediated via inhibition of nuclear factor-kappaB (NF-kappaB), a pivotal transcriptional regulator in inflammation and repair.
10.1136/thx.2008.110304
Grant Details
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