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Flynn, A,Barry, F,O'Brien, T
2007
July
UC blood-derived mesenchyrnal stromal cells: an overview
Published
1
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characterization cytokine differentiation genomic isolation mesenchymal stromal cells pre-clinical umbilical cord blood UMBILICAL-CORD BLOOD HUMAN BONE-MARROW MOBILIZED PERIPHERAL-BLOOD GENE-EXPRESSION PROFILE MULTIPOTENT STEM-CELLS PROGENITOR CELLS ADIPOSE-TISSUE OBSTETRIC FACTORS IN-VITRO DIFFERENTIATION
The UC is a readily available source of blood that may be used for analysis and treatment. Some authors suggest that Within the UC blood (UCB) are cells with potential for differentiation down mesenchymal lineages. Isolation and characterization of these cells has been accomplished in some centers. Differentiation of these cells down multiple lineages has been documented. Surface marker expression and gene expression profiling has been performed, and mesenchymal stromal cells (MSC) from BM and adipose tissue have been compared with those derived from UCB. The use of UCB-derived stein cells has been investigated in pre-clinical studies. As this field is rapidly advancing, this review summarizes the current state of our knowledge of MSC derived from UCB.
717
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DOI 10.1080/14653240701584578
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