Peer-Reviewed Journal Details
Mandatory Fields
OBoyle, CJ,OHanlon, DM,Kerin, MJ,Barry, MK,Given, HF
1996
October
Eur J Surg Oncol
Laparoscopic oophorectomy: A prospective evaluation in pre-menopausal breast cancer with particular reference to incidence and severity of menopausal symptoms
Published
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Optional Fields
pre-menopausal breast cancer laparoscopic oophorectomy menopausal symptoms ADJUVANT CHEMOTHERAPY CYCLOPHOSPHAMIDE METHOTREXATE FLUOROURACIL TAMOXIFEN ZOLADEX TRIAL WOMEN
22
5
491
493
Laparoscopic oophorectomy offers potential advantages over other methods of ovarian ablation. In this prospective study the technique, complications and side-effects have been assessed in 69 consecutive patients. Menopausal symptoms were assessed using two scoring systems - the Kupperman index and the Women's Health Questionnaire. The serum beta oestradiol levels fell rapidly post-operatively (from 540 pmol/l to 25 pmol/l within 1 month). Menopausal symptoms were mild in 75% of patients and severe in none. Complications occurred in three patients. Laparoscopic oophorectomy has an important role to play in the management of pre-menopausal breast cancer and this study confirms that is well tolerated and gives good short-term results.
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