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McAnena, P;Lowery, A;Kerin, MJ
2018
January
Role of micro-RNAs in breast cancer surgery
Published
1
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BRCA2 MUTATION CARRIERS LYMPH-NODE METASTASIS CIRCULATING MICRORNAS TUMOR-SUPPRESSOR RECEPTOR STATUS NUCLEAR EXPORT UP-REGULATION EARLY-STAGE EXPRESSION CELLS
Background: The management of breast cancer has changed dramatically in the molecular era. Micro-RNAs can contribute to multiple facets of cancer surgery.Methods: This narrative review, based on years of research on the role of micro-RNAs, focused on the potential of these small, robust RNAs to influence all aspects of breast cancer surgery.Results: Micro-RNAs have a potential role as biomarkers in the diagnosis, prognosis and evaluation of response to therapy in breast cancer. They may also contribute to future therapeutic strategies.Conclusion: The molecular era has changed understanding of cancer. Micro-RNAs have the potential for use in personalized cancer strategies.
HOBOKEN
WILEY
0007-1323
19
30
10.1002/bjs.10790
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