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Mandatory Fields
Reviews
Beecher, SM;O'Leary, DP;McLaughlin, R;Kerin, MJ
2018
January
The Impact of Surgical Complications on Cancer Recurrence Rates: A Literature Review
Published
1
Optional Fields
POSTOPERATIVE INTRAABDOMINAL INFECTION LONG-TERM SURVIVAL BREAST-CANCER COLORECTAL-CANCER SITE INFECTION RISK-FACTORS VASCULAR-PERMEABILITY WOUND-INFECTION MAJOR SURGERY TUMOR-GROWTH
Introduction: The inflammatory response to a post-operative infection can increase the risk of tumour recurrence in cancer through the release of pro-inflammatory mediators. The aim of this study was review the literature to assess the relationship between post-operative complications and cancer recurrence. Methods: We performed a literature review of the mechanism of such an association and looked at evidence in different cancer subtypes. Results: A relationship has been identified for many cancer subtypes, and multiple theories have been proposed for the mechanism of this association. Methods to reduce post-operative complications may impact positively on cancer recurrence rates. Conclusion: This review demonstrates that wound complications after surgery can have significant implications for cancer patients. Strategies are required to minimize the risk of post-operative wound complications in patients undergoing cancer resection. (C) 2018 S. Karger GmbH, Freiburg
BASEL
KARGER
2296-5270
478
482
10.1159/000487510
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