Peer-Reviewed Journal Details
Mandatory Fields
OHANLON, DM;KERIN, MJ;KENT, P;MAHER, D;GRIMES, H;GIVEN, HF
1995
June
British Journal Of Cancer
AN EVALUATION OF PREOPERATIVE CA-5-3 MEASUREMENT IN PRIMARY BREAST-CARCINOMA
Published
WOS: 43 ()
Optional Fields
MONOCLONAL-ANTIBODIES CANCER PATIENTS ANTIGEN LEVELS CA15-3 TUMORS DF3
71
1288
1291
In this study of 500 patients with breast carcinoma, we have prospectively assessed the role of preoperative CA 15-3 as a marker of disease burden over a 7 year period. CA 15-3 levels at presentation correlate with stage of disease, tumour size, lymph node status, the presence of metastases and lymphocyte infiltration into the tumour. CA 15-3 alone is not an independent prognostic indicator, although a serum level of > 40 U ml(-1) has a positive predictive value of 83% for the presence of advanced disease. We recommend the routine use of this marker in the preoperative assessment of primary breast carcinoma.
0007-0920
Grant Details
Publication Themes