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Reviews
Slattery, MM;Morrison, JJ
2002
November
Preterm delivery
Published
1
Optional Fields
LOW-BIRTH-WEIGHT HUMAN MYOMETRIAL CONTRACTILITY RANDOMIZED CONTROLLED TRIAL BROAD-SPECTRUM ANTIBIOTICS POLYMERASE CHAIN-REACTION INFANTS BORN ANTENATAL CORTICOSTEROIDS BACTERIAL VAGINOSIS COCAINE USE IN-VITRO
Preterm delivery and its short-term and long-term sequelae constitute a serious problem in terms of mortality, disability, and cost to society. The incidence of preterm delivery, which has increased in recent years, is associated with various epidemiological and clinical risk factors. Results of randomised controlled trials suggest that attempts to reduce these risk factors by use of drugs are limited by side-effects and poor efficacy. An improved understanding of the physiological pathways that regulate uterine contraction and relaxation in animals and people has, however, helped to define the complex processes that underlie parturition (term and preterm), and has led to new scientific approaches for myometrial modulation. The continuing elucidation of the mechanisms that regulate preterm labour, combined with rigorous clinical assessment, offer hope for future solutions.
NEW YORK
ELSEVIER SCIENCE INC
0140-6736
1489
1497
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