his study aimed to examine how sexuality, shame and perfectionism predicts the frequency of intrusive thoughts (ITs) in a student sample and the interaction effects between these factors. It also aimed to evaluate the experience of intrusive thoughts in an LGBTQA+ population in comparison to their heterosexual counterparts. The occurrence of intrusive thoughts is a universal phenomenon and plays a central role in the understanding of how obsessions are developed and maintained. Salvoskis’s ‘appraisal’ model proposes that ‘normal’ unwanted intrusive thoughts develop into a clinical obsession when an individual interprets and appraises them negatively. 178 university students completed a series of standardized measures. A hierarchical regression revealed that sexual orientation and shame are key risk factors for the frequency of intrusive thoughts, and that shame mediates the relationship between perfectionism and these intrusions. Regression analysis also demonstrated that obsessive-compulsive symptoms are shown to be predicted by depression, perfectionism and shame. Profile analysis showed the LGBTQA+ sample to have higher ratings on each of the psychological variables examined, but only significantly so on measures of intrusive thoughts, obsessive-compulsive symptoms and depression.