Peer-Reviewed Journal Details
Mandatory Fields
O'Neill, HS;Gallagher, LB;O'Sullivan, J;Whyte, W;Curley, C;Dolan, E;Hameed, A;O'Dwyer, J;Payne, C;O'Reilly, D;Ruiz-Hernandez, E;Roche, ET;O'Brien, FJ;Cryan, SA;Kelly, H;Murphy, B;Duffy, GP
2016
July
Advanced Materials (Deerfield Beach, Fla.)
Biomaterial-Enhanced Cell and Drug Delivery: Lessons Learned in the Cardiac Field and Future Perspectives
Published
Altmetric: 17WOS: 17 ()
Optional Fields
ACUTE MYOCARDIAL-INFARCTION CHRONIC HEART-FAILURE LEFT-VENTRICULAR FUNCTION MESENCHYMAL STEM-CELLS CHRONIC ISCHEMIC CARDIOMYOPATHY GELATIN METHACRYLATE HYDROGELS RGD MODIFIED ALGINATE EXTRACELLULAR-MATRIX 6-MINUTE WALK INTRAMYOCARDIAL INJECTIONS
28
5648
5661
Heart failure is a significant clinical issue. It is the cause of enormous healthcare costs worldwide and results in significant morbidity and mortality. Cardiac regenerative therapy has progressed considerably from clinical and preclinical studies delivering simple suspensions of cells, macromolecule, and small molecules to more advanced delivery methods utilizing biomaterial scaffolds as depots for localized targeted delivery to the damaged and ischemic myocardium. Here, regenerative strategies for cardiac tissue engineering with a focus on advanced delivery strategies and the use of multimodal therapeutic strategies are reviewed.
0935-9648
10.1002/adma.201505349
Grant Details
Publication Themes