Peer-Reviewed Journal Details
Mandatory Fields
Alzahrani, A,Mirallai, SI,Chalmers, BA,McArdle, P,Aldabbagh, F
2018
June
Organic & Biomolecular Chemistry
Synthesis of N-[(dialkylamino)methyl]acrylamides and N-[(dialkylamino) methyl]methacrylamides from Schiff base salts: useful building blocks for smart polymers
Published
Optional Fields
DIMETHYL(METHYLENE)AMMONIUM IODIDE AQUEOUS-SOLUTION MANNICH SENSITIVITY DERIVATIVES AMINALS ACID
16
4108
4116
The traditional thermal Mannich reaction is unsuitable for preparing polymerizable N-methylene amino substituted acrylamides and methacrylamides. Herein we provide a facile multi-gram high yield synthesis of these monomeric precursors to stimuli-responsive polymers by the addition of acrylamides and methacrylamides onto in situ generated or freshly isolated methylene Schiff base (iminium) salts. The X-ray crystal structure of the hydrated iminium salt, 1-(hydroxymethyl)azocan-1-ium chloride and monomer center dot HCl salt (N-[(azocan-1-yl)methyl]prop-2-enamide hydrochloride) is described.
10.1039/c8ob00811f
Grant Details
Publication Themes