Peer-Reviewed Journal Details
Mandatory Fields
Kelada, M,Walsh, JMD,Devine, RW,McArdle, P,Stephens, JC
2018
May
Beilstein Journal Of Organic Chemistry
Synthesis of pyrazolopyrimidinones using a "one-pot" approach under microwave irradiation
Published
Altmetric: 9WOS: 2 ()
Optional Fields
microwave-assisted synthesis nitrogen-fused heterocycle one-pot pyrimidinone SOLVENT-FREE CONDITIONS REGIOSELECTIVE SYNTHESIS KDM5 INHIBITORS IDENTIFICATION
14
1222
1228
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1, 5-a] pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.
10.3762/bjoc.14.104
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