Peer-Reviewed Journal Details
Mandatory Fields
Mizuta, S;Verhoog, S;Engle, KM;Khotavivattana, T;O'Duill, M;Wheelhouse, K;Rassias, G;Medebielle, M;Gouverneur, V
2013
February
Journal Of The American Chemical Society
Catalytic Hydrotrifluoromethylation of Unactivated Alkenes
Published
Altmetric: 2WOS: 238 ()
Optional Fields
LIGHT PHOTOREDOX CATALYSIS MEDICINAL CHEMISTRY ORGANIC-SYNTHESIS TERMINAL ALKENES BOND FORMATION TRIFLUOROMETHYLATION EFFICIENT FLUORINE RADICALS ACIDS
135
2505
2508
A visible-light-mediated hydrotrifluoromethylation of unactivated alkenes that uses the Umemoto reagent as the CF3 source and MeOH as the reductant is disclosed. This effective transformation operates at room temperature in the presence of 5 mol % Ru(bpy)(3)Cl-2; the process is characterized by its operational simplicity and functional group tolerance.
0002-7863
10.1021/ja401022x
Grant Details
Publication Themes