Peer-Reviewed Journal Details
Mandatory Fields
Moran, C,Doyle, F,Sulaiman, I,Bennett, K,Greene, G,Molloy, GJ,Reilly, RB,Costello, RW,Mellon, L
2017
October
Psychology & Health
The INCA (TM) (Inhaler Compliance Assessment (TM)): A comparison with established measures of adherence
Published
Altmetric: 13WOS: 4 ()
Optional Fields
chronic obstructive pulmonary disease (COPD) adherence inhaler electronic monitor construct validity predictive validity OBSTRUCTIVE PULMONARY-DISEASE MILD COGNITIVE IMPAIRMENT INSPIRATORY FLOW-RATE MEDICATION ADHERENCE POOR ADHERENCE CLAIMS DATA COPD NONADHERENCE VALIDATION INHALATION
32
1266
1287
Objective: To compare the Inhaler Compliance Assessment(TM) (INCA(TM)), a novel audio-recording device objectively measuring timing and proficiency of inhaler use, against established adherence measures, and explore its discriminant and predictive validity.Design: Prospective observational study; 184 chronic obstructive pulmonary disease (COPD) patients used an INCA(TM)-enabled salmeterol/fluticasone inhaler for one-month post-hospital discharge.Main outcome measures: INCA(TM) (Attempted, Attempted Interval, Actual) adherence correlated with Doses Used Rate, self-reported adherence and prescription refill for concurrent validity. Discriminant validity for reason for admission, cognition and lung function; predictive validity for health status and quality-of-life.Results: Rates of Attempted, Attempted Interval and Actual adherence were 59, 47 and 23%, respectively. Only 7% of participants had Actual adherence>80%. INCA(TM) variables significantly correlated with Doses Used Rate but not with self-report; Attempted and Attempted Interval were weakly associated with prescription refill. Higher cognitive and lung functioning groups had better INCA(TM) adherence. Attempted and Attempted Interval predicted health status, while Doses Used Rate predicted quality-of-life.Conclusion: INCA(TM) did not strongly correlate with self-report or prescription refill data. Discriminant and predictive validity demonstrated by INCA(TM) suggests the potential utility of the INCA(TM) as a method to identify intentional and unintentional adherence to inhaled medication and facilitate targeted intervention.
10.1080/08870446.2017.1290243
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