Peer-Reviewed Journal Details
Mandatory Fields
Allen NM, O'Brien M, Friel AM, Smith TJ, Morrison JJ
2007
February
American Journal Of Obstetrics And Gynecology
Expression and function of protease-activated receptor 4 in human myometrium.
Published
()
Optional Fields
196
2
1690
1696
Little is known about the presence or functional effects of protease-activated receptor subtypes in human uterine tissues. The aims of this study were as follows: (1) to investigate for protease-activated receptor-4 messenger RNA and protein expression in human myometrium, (2) to evaluate the effects of a specific protease-activated receptor-4 activating peptide (AYPGKF-NH2) on spontaneous human myometrial contractility in vitro, and (3) to examine the effects of a protease-activated receptor-4 antagonist (tcYPGKF-NH2) on thrombin-mediated uterine contractility.
10.1016/j.ajog.2006.09.027
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