Peer-Reviewed Journal Details
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Prendergast L, Sullivan KF.
2010
January
Nat Cell Biol
A GTPase switch maintains CENP-A at centromeric chromatin
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COMPLEX KINETOCHORE NUCLEOSOMES REQUIRES HJURP
12
12
1128
1130
The histone H3 variant CENP-A defines centromeric chromatin, but it has been unclear how CENP-A is stably maintained at centromeres. It has now been shown that the CENP-A licensing factor HsKNL2 and the small GTPases activating protein MgcRacGAP cooperate to promote the stability of newly loaded CENP-A at centromeres.
DOI 10.1038/ncb1210-1128
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