Peer-Reviewed Journal Details
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McDonnell, P., Liebschner, M.A.K., Tawackoli, W., McHugh, P.E.
2009
January
Medical Engineering And Physics
Vibration testing of trabecular bone architectures using rapid prototype models
Published
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Optional Fields
Structural dynamics Resonant frequency Cancellous bone Osteoporosis Bone micro-architecture VERTEBRAL CANCELLOUS BONE X-RAY ABSORPTIOMETRY ELASTIC PROPERTIES DENSITY NANOINDENTATION ADAPTATION SIMULATION DEPENDENCE PRECISION STIFFNESS
31
1
108
115
The purpose of this study was to investigate if standard analysis of the vibrational characteristics of trabecular architectures can be used to detect changes in the mechanical properties due to progressive bone loss. A cored trabecular specimen from a human lumbar vertebra was mu CT scanned and a three-dimensional, virtual model in stereolithography (STL) format was generated. Uniform bone loss was simulated using a surface erosion algorithm. Rapid prototype (RP) replicas were manufactured from these virtualised models with 0%, 16% and 42% bone loss. Vibrational behaviour of the RP replicas was evaluated by performing a dynamic compression test through a frequency range using an electro-dynamic shaker. The acceleration and dynamic force responses were recorded and fast Fourier transform (FFT) analyses were performed to determine the response spectrum. Standard resonant frequency analysis and damping factor calculations were performed. The RP replicas were subsequently tested in compression beyond failure to determine their strength and modulus. It was found that the reductions in resonant frequency with increasing bone loss corresponded well with reductions in apparent stiffness and strength. This suggests that structural dynamics has the potential to be an alternative diagnostic technique for osteoporosis, although significant challenges must be overcome to determine the effect of the skin/soft tissue interface, the cortex and variabilities associated with in vivo testing. (C) 2008 IPEM. Published by Elsevier Ltd. All rights reserved.
DOI 10.1016/j.medengphy.2008.04.012
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