Peer-Reviewed Journal Details
Mandatory Fields
Newland, B., Tai, H., Zheng, Y., Velasco, D., Di Luca, A., Howdle, S.M., Alexander, C., Wang, W. and Pandit, A.
2010
January
Chemical Communications
A Highly Effective Gene Delivery Vector - Hyperbranched Poly(2-(Dimethylamino) Ethyl Methacrylate) From In-situ Deactivation Enhanced ATRP
Published
()
Optional Fields
TRANSFER RADICAL POLYMERIZATION PAMAM DENDRIMERS CYTOTOXICITY COPOLYMERS COMPLEXES POLYMERS
46
26
4698
4700
A hyperbranched 2-(dimethylamino) ethyl methacrylate (DMAEMA) based polymer has been synthesised by a one-pot in situ deactivation enhanced atom transfer radical polymerisation (DE-ATRP); it exhibits much higher transfection ability than linear poly(DMAEMA) and is comparable to the well known branched poly(ethylene imine) (PEI) and the SuperFect (R) dendrimer but with lower cytotoxicity.
DOI 10.1039/c0cc00439a
Grant Details
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