Horizontal resolution sensitivity can significantly contribute to the uncertainty in predictions of meteorology and air-quality from a regional climate model. In the study presented here, a state-of-the-art regional scale atmospheric climate-chemistry-aerosol model REMOTE is used to understand the influence of spatial model resolutions of 1.0 degrees, 0.5 degrees and 0.25 degrees on predicted meteorological and aerosol parameters for June 2003 for the European domain comprising North-east Atlantic and Western Europe. Model precipitation appears to improve with resolution while wind speed has shown best results for 0.25 degrees resolution for most of the stations compared with ECAD data. Low root mean square error and spatial bias for surface pressure, precipitation and surface temperature show that the model is very reliable. Spatial and temporal variation in black carbon, primary organic carbon, sea-salt and sulphate concentrations and their burden are presented. In most cases, chemical species concentrations at the surface show no particular trend or improvement with increase in resolution. There has been a pronounced influence of horizontal resolution on the vertical distribution pattern of some aerosol species. Some of these effects are due to the improvement in topographical details, flow characteristics and associated vertical and horizontal dynamic processes. The different sink processes have contributed very differently to the various aerosol species in terms of deposition (wet and dry) and sedimentation which are strongly linked to the meteorological processes. Overall, considering the performance of meteorological parameters and chemical species concentrations, a horizontal model resolution of 0.5 degrees is suggested to achieve reasonable results within the limitations of this model. (C) 2011 Elsevier B.V. All rights reserved.