Conference Publication Details
Mandatory Fields
Mahony, S,Smith, TJ,McInerney, JO,IEEE COMPUTER SOCIETY
A new approach to gene prediction using the self-organizing map
PROCEEDINGS OF THE 2003 IEEE BIOINFORMATICS CONFERENCE
2003
March
Published
1
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Optional Fields
CODON USAGE
444
445
In this poster we present a gene prediction approach based on the Self-Organizing Map that has the ability to automatically identify all the major patterns of content variation within a genome. The genome may then be scanned for regions displaying the same properties as one of these automatically identified models. Even using a relatively simple coding measure (codon usage), this method can predict the location of protein-coding sequences with a reasonably high accuracy. We also show other advantages of the approach, such as the ability to indicate genes that contain frame-shifts. We believe that this method has the potential to become a useful addition to the genome annotation process.
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