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Mohammad, A,Lohan, D,Bergin, D,Mooney, S,Newell, J,O'Donnell, M,Coughlan, RJ,Carey, JJ
2014
January
Journal Of Clinical Densitometry
The Prevalence of Aortic Calcification on Vertebral Fracture Assessment Imaging Among Patients With Rheumatoid Arthritis
Published
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Abdominal aortic calcification cardiovascular disease DXA rheumatoid arthritis VFA C-REACTIVE PROTEIN INCIDENT MYOCARDIAL-INFARCTION CORONARY-ARTERY CALCIUM INTIMA-MEDIA THICKNESS CARDIOVASCULAR EVENTS COMPUTED-TOMOGRAPHY HEART-DISEASE RISK-FACTORS ATHEROSCLEROSIS ASSOCIATION
17
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Patients with rheumatoid arthritis (RA) are at increased risk of osteoporosis (OP) and cardiovascular disease (CVD). Dual-energy X-ray absorptiometry scans have been validated for identifying patients with RA at risk for fracture. Reliable CVD risk stratification remains an unmet need in this population. Vertebral fracture assessment (VFA)-detected abdominal aortic calcification (AAC) has been validated as a marker of CVD in other populations, but the prevalence among patients with RA is unknown. In this study, we determined the prevalence and severity of AAC on VFA scans in a cohort of patients with RA. AAC was detected in 211 of the 603 (35%) eligible subjects; 24% were graded as severe. In multivariable analyses, the presence of AAC was significantly associated with longer disease duration and higher disease activity (p<0.05). Further studies are needed on the relationship between AAC and CVD in patients with RA.
10.1016/j.jocd.2013.02.014
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